Ormeño, Fernando Barrientos, Camila Ramirez, Santiago Ponce, Iván Valenzuela, LucÃa Sepúlveda, SofÃa Bitar, Mainá Kemmerling, Ulrike Machado, Carlos Renato Cabrera, Gonzalo Galanti, Norbel All rights reserved.Įxpression and the Peculiar Enzymatic Behavior of the Trypanosoma cruzi NTH1 DNA Glycosylase Collectively, these data confirm a role for Nth in base excision repair in mycobacteria and further highlight a novel interplay between the Nth and Nei homologues in spontaneous mutagenesis. Furthermore, no differential emergence of the common rifampicin resistance conferring genotypes were noted. Deletion of nth together with the fpg homolgues did not result in any growth/survival defects or changes in mutation rate. Deletion of nth individually results in increased UV-induced mutagenesis and combinatorial deletion with the nei homologues results in reduced survival under oxidative stress conditions and an increase in spontaneous mutagenesis to rifampicin.
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Msm mutants lacking nei1, nei2 and nth individually or in combination did not display aberrant growth in broth culture. Using an Escherichia coli nth deletion mutant, we confirm the functionality of the mycobacterial nth gene in the base excision repair pathway. In this study we assess the contribution of Nei and Nth DNA repair enzymes in Mycobacterium smegmatis (Msm), which retains a single nth homologue and duplications of the Fpg (fpg1 and fpg2) and Nei (nei1 and nei2) homologues.
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Formamidopyrimidine (Fpg/MutM/Fapy) and EndonucleaseVIII (Nei) constitute the Fpg/Nei family of DNA glycosylases and together with EndonucleaseIII ( Nth) are central to the base excision repair pathway in bacteria. DNA damage by host-derived reactive oxygen/nitrogen species is hypothesized to be critical for the mutagenic process in Mtb thus, highlighting an important role for DNA repair enzymes in maintenance of genome fidelity. The increased prevalence of drug resistant strains of Mycobacterium tuberculosis (Mtb) indicates that significant mutagenesis occurs during tuberculosis disease in humans. Moolla, Nabiela Goosens, Vivianne J Kana, Bavesh D Gordhan, Bhavna G The contribution of Nth and Nei DNA glycosylases to mutagenesis in Mycobacterium smegmatis. Also included is a compendium of formulae and properties of the theta operator and generalized hypergeometric functions which is complete enough to make the report self-contained. The superiority of the two methods shown over the standard method is demonstrated by using all three of the methods to work out several examples. For completeness, the analysis of the differential equation to determine whether the point of expansion is an ordinary point or a regular singular point is included. The use of the theta-operator method and generalized hypergeometric functions in obtaining solutions to nth-order linear ordinary differential equations is explained.
INVENTOR MESH ENABLER NOT CREATING SOLID SERIES
Some efficient methods for obtaining infinite series solutions of n-th order linear ordinary differential equations The result shows that the nth-order harmonic of the Bessel beam, like its fundamental component, is radially limited diffracting, and that the main beamwidth of the nth-order harmonic is exactly 1/n times that of the fundamental. We investigate theoretically the nonlinear propagation of the limited diffraction Bessel beam in nonlinear media, under the successive approximation of the KZK equation. Higher- order harmonics of limited diffraction Bessel beams It is pointed out that the many-ghost imaging phenomenon is an observable physical effect induced by higher order coherence or higher order correlations of optical fields.« less It is found that themore » visibility of the ghost images can be dramatically enhanced when the order of correlation becomes larger.
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We investigate the visibility of the ghost images in the scheme and obtain the upper bounds of the visibility for the Nth-order correlated thermal-light ghost imaging. We show that it is possible to produce N-1 ghost images of an object at different places in a nonlocal fashion by means of a higher order correlated imaging process with an Nth-order correlated thermal source and correlation measurements. We obtain the Gaussian thin lens equations in the many-ghost imaging protocol. In this paper, we propose a theoretical scheme of many-ghost imaging in terms of Nth-order correlated thermal light. Liu Yingchuan College of Mathematics and Physics, University of South China, Hengyang 421001 Kuang Leman Theoretical scheme of thermal-light many-ghost imaging by Nth-order intensity correlation